This pleasant and amusing little way of passing a couple of hours takes place in a universe not unlike the one we may remember from “Who Framed Roger Rabbit?” The major difference is that here the cartoon characters (carefully not referred to as “toons”) are all straight out of the Warner Brothers animation labs, are all old friends (unlike Roger and Jessica Rabbit, who were invented strictly for the earlier movie), and whose antics can be counted on to mirror those we remember from old cartoons.

The Warner Bros. (there are two of them in the film) have hired a new Vice-President for Comedy, Kate Houghton (Jenna Elfman), who notices that it’s Bugs Bunny who brings in all the money and laughs, and so decides to dump Daffy Duck (though not his name, which the studio owns). You may suppose that the irrepressible Daffy will not go quietly into that good night. A security guard hired to escort him off the lot, one D. J. Drake (Brendan Fraser, who also gets to do the voice of the Tasmanian Devil and who also has a cameo as himself), instead manages to cause unintended havoc and is also fired by Houghton. Ultimately, he and Daffy set out on a road trip to Las Vegas to rescue his father, famous film (and real-life) super-spy Damien Drake (sometime James Bond Timothy Dalton), and to prevent the ubiquitous Acme Corporation’s evil Mr. Chairman (Steve Martin) from acquiring the fabulous Blue Monkey diamond, a supernatural artifact whose radiation will turn every human being on earth into blue monkeys. Meanwhile, Warner Bros. #1 and #2, noticing that many of Bugs’s best jokes don’t work without Daffy as a foil (“it’s duck season” … “no, it’s rabbit season” … “no, it’s rabbit season” … “no, it’s duck season; shoot now!”), give Houghton until Monday to bring Daffy back, and she and Bugs too set out on a road trip to Vegas.

Many of the other Warner characters get to appear either as cameos (Taz, Shaggy and Scooby, Granny and Sylvester and Tweety, the Road Runner; watch for the Warner Bros. cafeteria scene) or as secondary characters (Wile E. Coyote as “desertus-agentus-idioticus” for the Acme Corporation, Marvin the Martian as another Acme plant — we also get to see his space ship the “Martian Maggot” in action again — Yosemite Sam running an Acme-funded casino in Vegas). We also get to visit Area 52 and encounter many filmic space visitors from an earlier era (see “The Man from Planet X” drown in a helmetful of popcorn; hear the giant ants from “Them” digging around somewhere in the background).

My biggest complaint? Like Bob Hoskins in “Roger Rabbit”, none of the major human actors in this film seems capable of reacting naturally (with appropriate facial expressions) to their cartoon counterparts. But maybe that’s normal in modern films and television; I’ve noticed recently that a lot of younger actors tend to have wooden expressions under any circumstances (Tom Welling in “Smallville” springs immediately to mind; Lance Guest who seemed to wear a mask all the way through “The Last Starfighter” seems to have disappeared from the scene).

But by and large this mix of human actors and traditional cartoon characters seems to work, at least as far as humor is concerned. See it and enjoy it.